Ketamine

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Buy Ketamine worldwide. Ketamine is a medication that is used to induce loss of consciousness, or anesthesia. It can produce relaxation and relieve pain in humans and animals.

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Why is Ketamine Used Medically?

  • Ketamine can provide pain relief and short-term memory loss (for example, amnesia of a medical procedure).
  • In surgery, it is used an induction and maintenance agent for sedation and to provide general anesthesia.
  • It has also been used for pain control in burn therapy, battlefield injuries, and in children who cannot use other anesthetics due to side effects or allergies.

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Pharmacology of Ketamine

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors. It disrupts the neurotransmitter (brain chemical) glutamate.

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How is Ketamine Abused?

In addition to its legal, medical uses, ketamine and and synthesized analogs have become drugs of abuse with hallucinogenic properties. It has also been used as a “date rape” drug.

When abused, it is typically insufflated (“snorted” up the nose) in social situations. It is also injected, consumed orally as a liquid, or smoked in marijuana or tobacco. It is frequently abused in combination with other substances, such as cocaine or amphetamines. Use with multiple drugs has been fatal.

When misused, it is often sourced via the illegal diversion of prescription products, but analogs may be found on the streets.

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How Quickly Does Ketamine Work?

  • An injection yields a quick response, with effects occurring in seconds to minutes.
  • “Snorting” leads to effects in roughly 5 to 15 minutes (this is the most common method of abuse).
  • Oral consumption requires between 5 and 30 minutes.

The effects of abuse typically last 1 to 2 hours, but the users judgement, senses and coordination may be affected for up to 24 hours or longer. Sensations the user may seek include floating, stimulation and visual effects.

Overdose

  • Benzodiazepines such as lorazepam may be used if needed for seizures, excitation, or muscle rigidity.
  • Respiratory support is rarely needed, but assisted ventilation or supplemental oxygen may be required. Respiratory depression may be more likely if combined with sedatives.